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Guidelines for treating neuropsychiatric symptoms of Huntington’s disease were published in November 2018 in the Journal of Huntington’s Disease. [ 1 , 2 ]. GUIDELINES FOR AGITATION IN HUNTINGTON’S DISEASE (HD). Identify and treat comorbid medical conditions that can precipitate acute agitation. Either a benzodiazepine or an antipsychotic drug is the preferred pharmacologic option for treating acute agitation that is not responsive to behavioral strategies. Antipsychotics or mood-stabilizing antiepileptic drugs can be used for chronic agitation characterized by recurrent and ongoing distress, or continuing threat of harm to self or others. Pain medication may prove helpful for agitation when other therapies have failed. Full story

20 April